Jessner's Lymphocytic Infiltration - Symptoms, Causes & Treatment
Medically reviewed by Dr. Anand S. Urhekar, MD, MD Pathology, Clinical Advisor · Last updated July 2026
A benign chronic condition producing smooth, non-scaly red or pink plaques on the face, neck and upper back, which may clear centrally to form rings. It fluctuates over months to years, often worsening with sun exposure, and must be distinguished from lupus erythematosus.
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Quick Answer
Jessner's lymphocytic infiltration causes smooth red or pink plaques without scale on the face, neck and upper back, often ring-shaped and photosensitive. It is benign and self-limiting but can persist for years. A biopsy and lupus blood tests are usually done to exclude cutaneous lupus. Treatment options include sun protection, topical or intralesional steroids, hydroxychloroquine and, in some cases, laser.
Symptoms
- Smooth red or pink plaques with no surface scale
- Ring or arc shapes from central clearing
- Face, neck and upper back
- Worsening with sun exposure
- No itch or only mild itching
Causes & Risk Factors
- Unknown; a benign accumulation of lymphocytes in the dermis
- Ultraviolet exposure as an aggravating factor
- Possible overlap with lupus erythematosus tumidus
Treatment & Management
- Strict daily sun protection
- Potent topical or intralesional corticosteroids
- Topical calcineurin inhibitors
- Hydroxychloroquine for persistent disease
- Pulsed dye laser in selected cases
When to See a Doctor
See a dermatologist about persistent red facial plaques. Biopsy and autoimmune blood tests are recommended to exclude cutaneous lupus, which requires different management.
Frequently Asked Questions
Is it lupus?
It is not, but the two look very similar and overlap histologically with lupus tumidus. Biopsy plus ANA and other autoimmune tests are standard before a firm diagnosis is made.
Does it cause scarring?
No. Jessner's infiltration resolves without scarring or pigment change, which is one of the features distinguishing it from discoid lupus.
Related Conditions
Medical References
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Medical Disclaimer: This information is for educational purposes only and is not intended as medical advice. The content on this page should not be used to diagnose or treat any health problem. Always consult with a qualified healthcare professional for proper medical evaluation, diagnosis, and treatment of your condition.