Works in any phone browserNo appNo installFree to start
Skin Infections
Featured Guide

Cellulitis: Skin Infection Symptoms & When to Seek Care

Understanding this common bacterial infection that can become serious if left untreated.

January 2, 2026Evidence-based
Share

Have a spreading red area?

Our AI analyzes skin concerns using clinical criteria in seconds.

Cellulitis is a common bacterial skin infection that affects the deeper layers of skin. While it's usually treatable with antibiotics, it can become serious if not addressed promptly. Recognizing the signs early is crucial for getting proper treatment.

What Is Cellulitis?

Cellulitis occurs when bacteria (usually Streptococcus or Staphylococcus) enter through a break in the skin and infect the deeper layers of skin and underlying tissue. It's not contagious to others.

Signs and Symptoms

  • Redness: Area of red skin that spreads and expands
  • Swelling: Affected area becomes puffy and swollen
  • Warmth: Skin feels hot to touch
  • Pain: Tenderness and pain in affected area
  • Skin tightness: Stretched, shiny appearance
  • Red streaks: May radiate from infected area
  • Fever and chills: In more severe cases
  • Blisters: May develop in some cases
  • Dimpled skin: "Orange peel" texture

Common Locations

  • Lower legs: Most common site
  • Feet: Especially in people with diabetes or athlete's foot
  • Arms and hands: Often after injury
  • Face: Can be particularly serious
  • Around wounds: Surgical sites, cuts, insect bites

How Bacteria Enter the Skin

  • Cuts, scrapes, or puncture wounds
  • Surgical incisions
  • Insect or animal bites
  • Athlete's foot or fungal infections (creates cracks)
  • Dry, cracked skin (especially on heels)
  • Eczema or dermatitis
  • IV drug use
  • Tattoos or piercings

Risk Factors

  • Weakened immune system: HIV, chemotherapy, immunosuppressants
  • Diabetes: Poor circulation and sensation in feet
  • Obesity: Increased risk
  • Lymphedema: Chronic swelling
  • Chronic venous insufficiency: Poor leg circulation
  • Previous cellulitis: Increases risk of recurrence
  • Skin conditions: Eczema, athlete's foot

Emergency Warning Signs

Seek emergency care immediately if you have:

  • High fever (above 38.5°C/101.3°F) with skin infection
  • Rapidly spreading redness (mark edges with pen to track)
  • Severe pain out of proportion to appearance
  • Numbness in affected area
  • Black or purple discoloration
  • Large blisters or skin breakdown
  • Confusion or altered mental state
  • Signs of sepsis: rapid heartbeat, rapid breathing, feeling very unwell

These may indicate necrotizing fasciitis or sepsis—life-threatening emergencies.

Cellulitis vs Other Conditions

ConditionKey Difference
DVT (blood clot)Usually one leg, less red, more deep pain
Contact dermatitisItchy, clearly defined borders, often bilateral
GoutUsually affects joints, especially big toe
Venous stasisBoth legs, brownish discoloration, chronic
AbscessLocalized, fluctuant (squishy), may need drainage

Treatment

Antibiotics

  • Oral antibiotics: For mild to moderate cases (7-14 days typically)
  • IV antibiotics: For severe cases or if oral treatment fails
  • Common antibiotics: Flucloxacillin, cephalexin, clindamycin
  • Complete the course: Even if you feel better

Supportive Care

  • Elevate affected limb: Reduces swelling
  • Rest: Avoid excessive activity
  • Pain relief: Paracetamol or ibuprofen
  • Cool compresses: May provide comfort
  • Mark the edges: Track if redness is spreading or shrinking

Prevention

  • Clean wounds promptly: Wash with soap and water
  • Cover cuts and scrapes: With clean bandages
  • Moisturize dry skin: Prevents cracking
  • Treat athlete's foot: Fungal infections create entry points
  • Protect skin: Wear gloves when gardening, long sleeves in brush
  • Manage underlying conditions: Diabetes, eczema, lymphedema
  • Check feet daily: Especially if diabetic
  • Compression stockings: For chronic swelling

When to See a Doctor

  • Red, warm, painful, swelling skin
  • Redness that is spreading
  • Any skin infection with fever
  • Previous cellulitis and symptoms returning
  • Wound that isn't healing normally
  • Weakened immune system with any skin infection

Related Articles

Sources

  1. CellulitisNHS UK (2024)
  2. CellulitisMayo Clinic (2024)
  3. Bacterial Skin InfectionsDermNet NZ (2024)

Medical Disclaimer: This article is for educational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions about a skin condition. If you think you may have a medical emergency, call your doctor or emergency services immediately.