What is Squamous Cell Carcinoma?
Squamous cell carcinoma (SCC) develops in the squamous cells that make up the middle and outer layers of your skin. It's the second most common skin cancer after basal cell carcinoma, with over 1 million cases diagnosed annually in the US.
Unlike BCC, SCC can be more aggressive and has the potential to spread to lymph nodes and other organs if left untreated. This makes early detection particularly important.
Warning Signs of SCC
See a doctor if you notice:
Firm, red nodule that may be tender
Flat sore with a scaly, crusted surface
Rough, scaly patch that bleeds or crusts
Wart-like growth that crusts or bleeds
Sore that doesn't heal within 3 weeks
New growth on a scar or chronic wound
Thickened, rough patch on the lip
SCC vs BCC: Key Differences
SCC
- • Grows faster (weeks-months)
- • Can spread to lymph nodes
- • Often rough, scaly texture
- • Higher risk in immunocompromised
BCC
- • Grows slowly (months-years)
- • Rarely spreads
- • Often pearly, waxy appearance
- • Very low metastasis risk
Risk Factors
Cumulative sun exposure
Primary cause
Fair skin, light eyes
Higher susceptibility
History of sunburns
Increased risk
Tanning bed use
70% higher risk
Weakened immune system
Much higher risk
Previous SCC or BCC
10x higher risk
Frequently Asked Questions
Medical Disclaimer
This article is educational only. Only a dermatologist can diagnose SCC. Seek professional evaluation for any suspicious growths.